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在体内CRISPR查确定Ptpn2为癌症免疫治疗标

Robert T Manguso1,2,3, Hans W Pope1,3, Margaret D Zimmer1,3

  • 1Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

Nature
|July 21, 2017
PubMed
概括

研究人员在小鼠中使用CRISPR-Cas9查,以找到改善癌症免疫治疗的新方法. 在瘤中删除PTPN2基因增强了免疫反应,为癌症治疗提供了潜在的新点.

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