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果糖-1,6-双酸和阿尔多酶通过AMPK传感葡萄糖

Chen-Song Zhang1, Simon A Hawley2, Yue Zong1

  • 1State Key Laboratory for Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Fujian 361102, China.

Nature
|July 21, 2017
PubMed
概括

阿尔多酶感知葡萄糖水平以激活AMP激活蛋白激酶 (AMPK) 独立于AMP/ADP. 这种机制涉及果糖-1,6-双酸盐 (FBP) 与阿尔多酶结合,调节葡萄糖剥夺期间的AMPK激活.

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