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生物吸收性支架:寻求无事件溶解

Raffaele Piccolo1, Peter Jüni2, Stephan Windecker1

  • 1Department of Cardiology, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.

Lancet (London, England)
|July 23, 2017
PubMed
概括

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Bioavailability Enhancement: Drug Stability Enhancement and GI Retention01:05

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
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