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Updated: Feb 25, 2026

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基底状态的雌性ES细胞的衍生,维护配体衍生的DNA甲基化

Masaki Yagi1, Satoshi Kishigami2, Akito Tanaka1

  • 1Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.

Nature
|July 27, 2017
PubMed
概括

在小鼠胚胎干细胞 (ES细胞) 衍生中使用的两个小分子 (2i) 消除了基因组印记. 虽然这些细胞可以分化,但它们显示出发育缺陷,突出显示出需要改进的衍生方法.

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