在半合成生物体中复制非自然基对的结构-活动关系和优化

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Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
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Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

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Aaron W Feldman1, Floyd E Romesberg1

  • 1Department of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|August 11, 2017
PubMed
概括

研究人员为半合成生物 (SSO) 开发了新的非自然基对 (UBP),以存储更多信息. 四种新型的UBP在体内改善了DNA保留,使SSO技术超越了自然的遗传限制.

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