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The Helsinki Rat Microsurgical Sidewall Aneurysm Model
Published on: October 12, 2014
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2000年至2014年芬兰腹腔动脉瘤治疗的基于人口的研究
Matti T Laine1, Sani J Laukontaus2, Reijo Sund2
1From Department of Vascular Surgery, University of Helsinki and Helsinki University Hospital, Finland (M.T.L., S.J.L., P.S.A., I.K., A.A., M.V.); Center for Research Methods, Department of Social Research, University of Helsinki, Finland (R.S.); and Institute of Clinical Medicine, University of Eastern Finland, Kuopio (R.S.). matti.laine@hus.fi.
Circulation
|August 13, 2017
概括
在芬兰,腹动脉动脉瘤 (AAA) 破裂的发生率下降,随着选择性和紧急修复的治疗结果的改善. 增加内血管动脉瘤修复 (EVAR) 降低了短期死亡率,但长期EVAR死亡率仍然很高.
科学领域:
- 血管外科手术
- 公共卫生
- 流行病学
背景情况:
- 腹腔大动脉瘤 (AAA) 破裂的死亡率很高.
- 据报道,AAA的患病率和破裂发生率正在下降.
- 内血管动脉瘤修复 (EVAR) 已成为AAA的首选治疗方法.
研究的目的:
- 评估AAA治疗趋势的变化对芬兰的选择性和紧急修复结果的影响.
- 分析采用EVAR对AAA治疗结果的影响.
主要方法:
- 来自芬兰卫生与福利研究所的AAA患者数据的回顾性分析 (2000-2014).
- 包括芬兰统计局同期的死亡数据.
- 综合数据分析以评估治疗趋势和结果.
主要成果:
- 破裂AAA的年均发病率显著下降.
- 紧急AAA修复的30天死亡率为39. 4%.
- 选择性AAA修复量增加,EVAR变得占主导地位;选择性修复的30天死亡率从6. 3%降至2. 7%.
- 与开放性修复相比,EVAR后的长期死亡率更高,EVAR患者中AAA相关的晚期死亡比例更高.
结论:
- 在65岁以上的男性中,AAA破裂发生率下降可能是由于患病率下降.
- 选择性和紧急AAA修复的治疗结果有所改善.
- 虽然EVAR降低了短期死亡率,但其长期死亡率高于开放性修复,可能受患者选择的影响.
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