乳性疾病和非乳性谷蛋白敏感性:一篇综述
Maureen M Leonard1,2, Anna Sapone1,2,3, Carlo Catassi1,2,4,5
1Center for Celiac Research and Treatment, Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Boston, Massachusetts.
JAMA
|August 16, 2017
概括
与质相关的疾病如乳病和非乳敏感性是常见的. 在无质饮食之前准确诊断对于有效的长期管理和监测潜在并发症至关重要.
科学领域:
- 胃肠病学
- 免疫学
- 饮食医学
背景情况:
- 与质相关的疾病越来越普遍.
- 许多人自行诊断并采用无质饮食.
- 由于症状重叠,难以区分乳性疾病和非乳性谷蛋白敏感性.
研究的目的:
- 审查目前关于查,诊断和治疗乳病和非乳敏感性的证据.
- 强调准确诊断对于适当的患者管理的重要性.
- 强调饮食开始对诊断准确性的影响.
主要方法:
- 对与质有关的疾病的最新科学文献的审查.
- 对乳病和非乳敏感性的诊断标准的分析.
- 讨论临床表现,遗传标记和自身抗体.
主要成果:
- 乳病是一种免疫介导的肠病,具有特定的遗传和血清标志物.
- 缺乏有效的生物标志物,使诊断和研究变得复杂.
- 在临床上无法区分乳病和非乳敏感症的症状.
- 在实施无质饮食之前,必须进行乳病查以进行准确的检测.
结论:
- 乳性疾病和非乳性谷蛋白敏感性是需要无谷蛋白饮食的常见疾病.
- 区分这两个条件对于适当的长期管理至关重要.
- 患有乳病的患者需要密切监测其食,营养状况和并发症.
相关概念视频
Taste Buds and Receptors
5.5K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
5.5K
Other Disorders of Digestive System
1.6K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.6K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
960
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
960
Glucose Transporters
27.7K
Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
27.7K
Assessment of the Gastrointestinal System I: Subjective Data
728
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
728
Autoimmune Disorders
2.0K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
2.0K


