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Updated: Apr 15, 2026

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells
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Published on: February 8, 2018

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将CMTM6和CMTM4确定为PD-L1蛋白调节剂

Riccardo Mezzadra1, Chong Sun1, Lucas T Jae2

  • 1Division of Molecular Oncology &Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Nature
|August 17, 2017
PubMed
概括

研究人员发现了CMTM6,一种调节转移性癌症PD-L1表达的蛋白质. CMTM6稳定了PD-L1,增强了其抑制T细胞反应的能力,为癌症治疗提供了新的点.

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