1978年和1986年在圣托马斯医院的母性红疹:支持扩大红疹疫苗接种计划
Lancet (London, England)
|July 11, 1987
概括
1978年和1986年的红疹流行病在1986年显示出较少的母性红疹病例. 加强疫苗接种策略,包括学前免疫接种,对于根除红疹至关重要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
背景情况:
- 红疹疫情对孕妇和胎儿构成风险.
- 红疹疫苗接种计划旨在预防先天性红疹综合征.
- 评估红疹疫情对产前患者的影响对于公共卫生战略至关重要.
研究的目的:
- 为了比较1978年和1986年红疹流行病的影响.
- 评估现有的红疹疫苗接种策略的有效性.
- 建议改善红疹根除的方法.
主要方法:
- 两次红疹流行时期 (1978年和1986年) 的产前诊所数据的回顾性分析.
- 对母乳红疹病例数和患者调查的比较.
- 在孕妇中评估疫苗接种史和敏感性.
主要成果:
- 母亲红疹病例显著减少,从1978年的17例降至1986年的1例.
- 尽管病例较少,但在两年流行期间,大量资源用于调查.
- 显著的比例的孕妇仍然容易感染红疹,记录的疫苗接种史很少.
结论:
- 目前的红疹疫苗接种计划需要扩大.
- 建议将MMR联合疫苗扩大到学龄前儿童的疫苗接种范围.
- 增加疫苗接种覆盖率对于实现红疹根除至关重要.
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