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Updated: Feb 23, 2026

NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells
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Published on: January 12, 2020

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在癌症中,NF-κB c-Rel对调控性T细胞免疫检查点至关重要

Yenkel Grinberg-Bleyer1, Hyunju Oh1, Alexis Desrichard2

  • 1Department of Microbiology & Immunology, College of Physicians & Surgeons, Columbia University, New York, NY 10032, USA.

Cell
|September 9, 2017
PubMed
概括

在调节性T细胞 (Tregs) 中抑制NF-κBc-Rel通路会减缓黑色素瘤的生长. 这种方法通过减少Treg介导的免疫抑制来增强抗PD-1免疫疗法,为癌症治疗提供了新的策略.

关键词:
在 NF-κB癌症免疫疗法监管T细胞

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