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Updated: Jun 10, 2026

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures
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Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Published on: January 19, 2019

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修正"由酸DNA构建的银纳米组件"

Subhadeep Roy, Magdalena Olesiak, Shiying Shang

    Journal of the American Chemical Society
    |September 14, 2017
    PubMed
    概括

    No abstract available in PubMed .

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    相关概念视频

    Base Excision Repair01:54

    Base Excision Repair

    One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
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    Long-patch Base Excision Repair01:02

    Long-patch Base Excision Repair

    Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are: