在患有后病毒性疲劳综合征的患者中慢性肠道病毒感染
G E Yousef1, E J Bell, G F Mann
1Department of Pathology, St Mary's Hospital Medical School, London.
Lancet (London, England)
|January 23, 1988
概括
慢性肠道病毒感染在后病毒性疲劳综合征 (PVFS) 中很常见. 在血清中检测肠道病毒抗原是PVFS患者的有效诊断方法.
科学领域:
- 病毒学 病毒学
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
背景情况:
- 后病毒性疲劳综合征 (PVFS) 是一种经常在病毒感染后出现的衰弱状况.
- 持续性病毒感染在PVFS病原体中的作用仍在调查中.
研究的目的:
- 调查PVFS患者中肠道病毒感染的患病率.
- 评估检测PVFS诊断血清中的肠道病毒抗原的实用性.
主要方法:
- 从便样本中分离病毒,并使用特定的单克隆抗体在血清中检测肠道病毒VP1抗原.
- 与VP1抗原检测相关的IgM复合体存在的分析.
- 阳性病毒培养的患者的长度随访.
主要成果:
- 从22%的PVFS患者中分离出肠道病毒,而对照组只有7%.
- 在51%的PVFS患者的血清中检测到肠道病毒VP1抗原,当IgM复合体存在时,阳性度更高.
- 一年后,持续性肠道病毒感染在一组患者中得到证实.
结论:
- 慢性肠道病毒感染是许多PVFS病例的重要因素.
- 血清肠道病毒抗原检测为调查PVFS提供了一种敏感和实用的方法.
相关概念视频
Stages of Infection
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Endocarditis IV: Nursing Management
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Arboviral Encephalitis
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Encephalitis ll: Pathophysiology
Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...


