通过水传播的非A,非B型肝炎
V Ramalingaswami1, R H Purcell
1Fogarty International Center, National Institutes of Health, Bethesda, Maryland.
Lancet (London, England)
|March 12, 1988
概括
通过水传播的非A,非B型肝炎 (NANB) 疫情主要影响年轻人. 孕妇面临严重的风险,包括致命的肝衰竭,强调需要清洁的水和卫生预防肝炎.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 水性非A,非B型肝炎 (NANB) 引起疫情,特别是在年轻人中.
- 这种疾病通常是轻微的,但孕妇的死亡率很高,原因是发性肝衰竭.
研究的目的:
- 描述由水传播的非A,非B型肝炎的流行病学,诊断和控制.
- 为了强调孕妇的严重程度和地理分布.
主要方法:
- 诊断依赖于与污染水的流行病学联系,不包括甲型和乙型肝炎.
- 肝脏活检显示了特有的组织学特征.
- 检测包括识别由患者抗体聚集的便中的类似病毒的颗粒.
主要成果:
- NANB在东南亚和印度普遍存在,在非洲和拉丁美洲有新兴的认可.
- 疫情表明青少年对年轻人的偏好.
- 在孕妇中观察到发性肝衰竭和高病例死亡率.
结论:
- 控制策略包括改善供水,卫生和个人/食品卫生.
- 用免疫球蛋白进行被动免疫可能会为脆弱人群提供保护.
- 早期诊断和干预对于管理NANB爆发至关重要.
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