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Updated: Aug 15, 2026

Multi-locus Variable-number Tandem-repeat Analysis of the Fish-pathogenic Bacterium Yersinia ruckeri by Multiplex PCR and Capillary Electrophoresis
10:33

Multi-locus Variable-number Tandem-repeat Analysis of the Fish-pathogenic Bacterium Yersinia ruckeri by Multiplex PCR and Capillary Electrophoresis

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通过使用限制片段长度多态的完整链接图来将定量特征分解为孟德尔因子

A H Paterson1, E S Lander, J D Hewitt

  • 1Department of Plant Breeding and Biometry, Cornell University, Ithaca, New York 14853.

Nature
|October 20, 1988
PubMed
概括

研究人员使用限制片段长度多态 (RFLP) 在番茄中绘制了定量特征位置 (QTL). 这一突破使复杂特征的基因剖析成为可能,进步了我们对植物和动物遗传的理解.

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相关概念视频

Monohybrid Crosses01:20

Monohybrid Crosses

Overview
Dihybrid Crosses01:18

Dihybrid Crosses

Overview
Pedigree Analysis01:35

Pedigree Analysis

Overview
Law of Segregation01:49

Law of Segregation

When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.
Law of Independent Assortment02:03

Law of Independent Assortment

While Mendel’s Law of Segregation states that the two alleles for one gene are separated into different gametes, a different question of how different genes are inherited remains. For example, is the gene for tall plants inherited with the gene for green peas? Mendel asked this question by experimenting with a dihybrid cross; a cross in which both parents are homozygous for two distinct traits resulting in an F1 generation that are heterozygous for both traits.
Chromosomal Theory of Inheritance01:39

Chromosomal Theory of Inheritance

In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”