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Updated: May 4, 2026

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
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通过CEST使用CoII2MRI探针进行比度pH成像

Agnes E Thorarinsdottir1, Kang Du1, James H P Collins2

  • 1Department of Chemistry, Northwestern University , Evanston, Illinois 60208, United States.

Journal of the American Chemical Society
|October 14, 2017
PubMed
概括

研究人员使用化学交换和转移 (CEST) 开发了一种基于2的新型探针用于比值pH成像. 这种双核过渡金属探测器提供了度独立的pH测量,对体内研究有希望.

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pH01:24

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The potential of hydrogen (pH) is a measure of the acidity or basicity of a water-based solution determined by the concentration of hydronium ions (H3O+). In one liter of pure water at neutral pH, there are 1×10−7 moles of hydronium ions. However, the extensive range of hydronium ion concentrations present in water-based solutions makes measuring pH in moles cumbersome. Therefore, a pH scale was developed to convert moles of hydronium ions into the negative logarithm of the hydronium...
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