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原生展开的FG重复稳定了核孔综合体的结构

Evgeny Onischenko1, Jeffrey H Tang1, Kasper R Andersen2

  • 1Department of Biology, Institute of Biochemistry, Eidgenössische Technische Hochschule Zürich, Otto-Stern-Weg 3, CH-8093 Zurich, Switzerland.

Cell
|October 17, 2017
PubMed
概括

酵母核孔综合体 (NPC) 中的氨酸-甘氨酸 (FG) 反复不仅仅是调节运输;它们还结合了支架核波林 (Nups) 并帮助NPC组装. 这揭示了FG重复在NPC架构中的新结构作用.

关键词:
在FG重复本质上是无序的领域核包裹核孔生物发生核孔复合体核孔结构蛋白质的相互作用

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