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单分子成像显示细胞表面热点的受体-G蛋白相互作用

Titiwat Sungkaworn1,2, Marie-Lise Jobin1,2, Krzysztof Burnecki3

  • 1Institute of Pharmacology and Toxicology, University of Würzburg, Versbacher Straße 9, 97078 Würzburg, Germany.

Nature
|October 19, 2017
PubMed
概括

G蛋白合受体 (GPCR) 和G蛋白在细胞膜上形成短暂的复合体. 特定的膜"热点"调节这些动态相互作用,影响GPCR信号.

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