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针对埃博拉病毒病患者的支持性护理的基于证据的指导方针
François Lamontagne1, Robert A Fowler2, Neill K Adhikari2
1Department of Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada; Centre de recherche du CHUS de Sherbrooke, Sherbrooke, QC, Canada.
改善埃博拉病毒病 (EVD) 爆发的支持性护理指南至关重要. 基于证据的建议侧重于补水,监测,测试,人员配置和疼痛管理,以减少埃博拉病毒病例死亡率.
科学领域:
- 传染性疾病
- 公共卫生
- 流行病学
背景情况:
- 2013-2016年西非埃博拉病毒病 (EVD) 爆发突显了患者护理的严重缺陷.
- 挑战包括缺乏设施,患者的犹和有限的支持性医疗护理,导致高初始病例死亡率 (> 70%).
研究的目的:
- 制定基于证据的指导方针,以在埃博拉治疗单位 (ETU) 提供最佳的支持性护理.
- 为管理未来埃博拉疫情提供最佳实践信息.
主要方法:
- 使用推评估,开发和评价 (GRADE) 方法.
- 根据现有证据制定了支持性护理指南.
主要成果:
- 主要建议强调系统监测患者,包括生命体征和液体平衡.
- 指导方针提倡口服和静脉注射水分,必要的生化检测,足够的人员,以及使用止痛药,包括阿片类药物来治疗疼痛.
结论:
- 实施这些基于证据的支持性护理指南可以改善患者的治疗结果,并减少埃博拉疫情期间的死亡率.
- 结构化的支持性护理对于减轻未来埃博拉疫情的影响至关重要.
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