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Updated: Feb 20, 2026

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野生老鼠肠道微生物促进宿主健康并改善疾病抵抗力

Stephan P Rosshart1, Brian G Vassallo1, Davide Angeletti2

  • 1Immunology Section, Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, DHHS, Bethesda, MD 20892, USA.

Cell
|October 24, 2017
PubMed
概括

野生小鼠肠道细菌改善了实验室小鼠的健康状况. 这种天然微生物组减少了炎症,增加了对抗流感和结直肠癌的存活率,

关键词:
细菌大肠直肠癌细胞因子这种感觉发生炎症流感 的产生的微生物组病毒野生老鼠

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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