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Updated: Feb 19, 2026

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells
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肠道微生物组调节了黑色素瘤患者对抗PD-1 免疫疗法的反应

V Gopalakrishnan1,2, C N Spencer2,3, L Nezi3

  • 1Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Science (New York, N.Y.)
|November 4, 2017
PubMed
概括

在黑色素瘤患者中,肠道微生物对抗编程细胞死亡1蛋白 (PD-1) 免疫疗法的反应产生影响. 受试者肠道微生物群多样性和细菌特异性较高,这表明与治疗疗效有联系.

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