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Updated: Feb 19, 2026

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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双重金属离子与催化RNA中的核基的内球协调

Xin Liu1, Yu Chen1, Carol A Fierke1

  • 1Departments of Chemistry and ‡Biological Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.

Journal of the American Chemical Society
|November 9, 2017
PubMed
概括

这项研究揭示了核酶P中的特定RNA基如何与金属离子相互作用以进行催化. 经过修改的RNA显示活性降低,金属救援实验证实了关键尿素基的直接协调.

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