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Updated: Aug 13, 2026

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胚胎干细胞中的基因向产生的纠正的HPRT基因的生殖线传播和表达

S Thompson1, A R Clarke, A M Pow

  • 1Department of Molecular Biology, University of Edinburgh, Scotland.

Cell
|January 27, 1989
PubMed
概括

基因向纠正了小鼠胚胎干细胞中的突变. 这种纠正成功地通过生殖线传播,证明了在小鼠中进行向基因改造的可行方法.

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