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Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
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Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
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从同位素合体构建块进行非同位素自组装

Marcel Rey1,2, Adam D Law3,4, D Martin A Buzza5

  • 1Institute of Particle Technology, Friedrich-Alexander University Erlangen-Nürnberg , Cauerstrasse 4, 91058 Erlangen, Germany.

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概括

研究人员通过使用聚N-异烯胺 (PNiPAm) 微凝创建了复杂的状颗粒排列,如链和方形. 这些微凝诱导了柔软的排斥性相互作用,使异形球体的非六角自我组装成为可能.

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科学领域:

  • 体科学
  • 软物质物理
  • 材料自组装

背景情况:

  • 球状的状颗粒通常会自组成六角格子.
  • 对于具有特定相互作用的同位素粒子,理论上已经预测了复杂的非六边形相,但缺乏实验实现.

研究的目的:

  • 通过实验研究微球与空气/水界面上的聚N-异烯胺 (PNiPAm) 微凝的相位行为.
  • 了解微凝如何影响体自我组装并使非六角结构的形成.

主要方法:

  • 在PNiPAm微凝的存在下研究了空气/水界面上的体微球的相位行为.
  • 使用最小能量计算和有限温度蒙特卡洛模拟来建模粒子相互作用和结构.
  • 分析实验数据以确定相互作用潜力和由此产生的组装模式.

主要成果:

  • 在PNiPAm微凝的存在下观察到一个复杂的相图,其中包括链条和方形安排.
  • 实验数据表明PNiPAm微凝在微球周围形成冠状体,诱导柔软的排斥作用.
  • 模拟准确地复制了观察到的复杂结构,使用实验推导的硬核-软肩潜在.

结论:

  • 证明了从同位体构建块复杂的非六边形合体组件的实验实现.
  • 通过微凝添加调整粒子间相互作用潜力, 展示了控制自我组装成异构模式的能力.
  • 证实了诱导软排斥肩在控制新型体阶段的作用.