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Updated: Feb 18, 2026

Real Time Monitoring of Intracellular Bile Acid Dynamics Using a Genetically Encoded FRET-based Bile Acid Sensor
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Real Time Monitoring of Intracellular Bile Acid Dynamics Using a Genetically Encoded FRET-based Bile Acid Sensor

Published on: January 4, 2016

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NRF1是一种ER膜传感器,对胆固醇平衡至关重要

Scott B Widenmaier1, Nicole A Snyder1, Truc B Nguyen1

  • 1Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard TH Chan School of Public Health, Boston, MA 02115, USA.

Cell
|November 18, 2017
PubMed
概括

核红细胞因子2相关因子-1 (Nrf1) 感知并控制内细胞网中的多余胆固醇. Nrf1 缺乏导致肝损伤,突出显示其在胆固醇平衡中的关键作用.

关键词:
其他类型没有胆固醇细胞内膜网免疫新陈代谢炎症发生肝脏代谢过程压力

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