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Genome Editing in Mammalian Cell Lines using CRISPR-Cas
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在基因组DNA中编程A•T到G•C的基因编辑,无需DNA裂变

Nicole M Gaudelli1,2,3, Alexis C Komor1,2,3, Holly A Rees1,2,3

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Nature
|November 22, 2017
PubMed
概括

科学家开发了腺基编辑器 (ABE) 来将DNA中的A•T转换为G•C基对. 通过精确的基因编辑,

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