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超性腺炎:诊断和治疗方面的进展

Ditte Marie Lindhardt Saunte¹, Gregor Borut Ernst Jemec¹

¹Department of Dermatology, Zealand University Hospital, Roskilde, Denmark; Health Sciences Faculty, University of Copenhagen, Denmark.

|November 29, 2017

概括

这是一种常见的皮肤疾病,通常未得到充分的治疗. 最近的进展提供了新的抗生素,生物和手术选择来控制HS的症状并改善患者的结果.

科学领域:

皮肤病学
免疫学
流行病学

背景情况:

补腺炎 (HS) 影响0.05%至4.10%的人口.
尽管这种疾病很常见,但许多HS患者接受的治疗却不够.
这可能导致严重的残疾和并发症,包括肥胖,代谢综合征,糖尿病和关节炎,并与全因死亡率的增加有关.

研究的目的:

审查HS的诊断,流行病学和治疗.
突出了过去五年在高频率管理方面取得的进展.

主要方法:

在2011年9月1日至2017年5月1日期间发表的治疗研究的PubMed,MEDLINE和EMBASE的综合文献搜索.
不包括评论,指导方针,会议摘要和不到10名患者的研究.
在多个搜索引擎中搜索HS指南.

主要成果:

脊髓炎的诊断依赖于病变形态,位置 (例如,下,沟) 和慢性.
流行病学数据显示HS比以前估计的更常见.
有效的治疗包括组合抗生素 (克林达米辛/里法辛,以埃尔塔因为基础的疗法),阿达利木马布和潜在的IL-1/IL-12向治疗.
手术技术和激光治疗对临床结果的证据有限.

结论:

腺炎是一种普遍的疾病,需要针对特定的病变类型和位置进行差异诊断.
目前和新兴的治疗方法包括药物 (抗生素,生物药物) 和手术.
需要进一步研究以确定手术和激光干预的临床结果.

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