通过抑制受体通过RIFIN对Plasmodium falciparum进行免疫逃避

¹Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.
²Laboratory of Immunochemistry, WPI Immunology Frontier Research Centre, Osaka University, Suita, Osaka 565-0871, Japan.
³Centre for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
⁴Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
⁵National Institute for Medical Research, Tanga Research Centre, Tanga, Tanzania.
⁶Laboratory of Protein Synthesis and Expression, Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
⁷Department of Molecular Protozoology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.
⁸Department of Medical Zoology, School of Medicine, Mie University, Tsu, Mie 514-8507, Japan.
⁹Department of Environmental Parasitology, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
¹⁰Division of Malaria Research, Proteo-Science Centre, Ehime University, Matsuyama, Ehime, 790-8577, Japan.
¹¹Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

⁰Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.

概括

疟疾寄生虫Plasmodium falciparum通过使用RIFIN蛋白来结合和抑制免疫细胞来逃避免疫系统. 这种免疫逃避机制可能会导致严重的疟疾病例.

概括