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增强线粒体蛋白质稳定降低了粉样β蛋白质毒性

Vincenzo Sorrentino1, Mario Romani1, Laurent Mouchiroud1

  • 1Laboratory for Integrative and Systems Physiology, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.

Nature
|December 7, 2017
PubMed
概括

线粒体应激反应是阿尔茨海默病的关键. 增强线粒体健康和蛋白质稳定可以减少粉样β聚合并延长阿尔茨海默病模型的寿命.

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