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Updated: May 3, 2026

Rescue and Characterization of Recombinant Virus from a New World Zika Virus Infectious Clone
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开发寨卡疫苗的传统与创新

Ernesto T A Marques1, Donald S Burke2

  • 1Graduate School of Public Health, and the Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA; Instituto Aggeu Magalhães, Department of Virology and Experimental Therapeutics, FIOCRUZ-Pernambuco, Brazil.

Lancet (London, England)
|December 9, 2017
PubMed
概括

No abstract available in PubMed .

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Vaccine Production01:23

Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
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