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Updated: Feb 16, 2026

Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
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一个光核心骨架的基于四的彩色生物直角探针的单色设计策略

Youngjun Lee1, Wansang Cho1, June Sung2

  • 1CRI Center for Chemical Proteomics, Department of Chemistry, Seoul National University , Seoul 08826, Korea.

Journal of the American Chemical Society
|December 15, 2017
PubMed
概括

研究人员使用单色的设计开发了新的化生物对角探针. 这些探测器能够在各种颜色中实现高光启动比率的充满活力,可靠的活细胞成像.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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