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Updated: Feb 16, 2026

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自然杀手细胞通过感知生长因子来控制瘤的生长

Alexander D Barrow1, Melissa A Edeling1, Vladimir Trifonov2

  • 1Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Cell
|December 26, 2017
PubMed
概括

血小板衍生生长因子 (PDGF-DD) 促进瘤生长,但NKp44对自然杀手细胞的识别会触发抗瘤免疫反应. 这种相互作用导致细胞因子的释放和瘤细胞生长的停止,提供了潜在的治疗点.

关键词:
一个NK单元NKp44 其他其他类型癌症细胞周期细胞因子增长因子免疫监测天生的淋巴细胞

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