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通过化学环境变化破坏DNAG四重复的稳定性 在瘤进展期间促进转录

Hisae Tateishi-Karimata1, Keiko Kawauchi1, Naoki Sugimoto1

  • 1Frontier Institute for Biomolecular Engineering Research (FIBER), ‡Faculty of Frontiers of Innovative Research in Science and Technology (FIRST), and §Graduate School of FIRST, Konan University , 17-1-20 minatojima-minamimachi, Kobe 650-0047, Japan.

Journal of the American Chemical Society
|December 30, 2017
PubMed
概括

水平会影响DNA G-四重复的稳定性,影响基因转录. 癌细胞中较低的会破坏G四重复的稳定性,在瘤进展过程中可能会增加基因转录.

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