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在与基质模拟物6 - 碳烯的转换过程中,Bacillus subtilis QueE中的一个中间基

Jarett Wilcoxen1, Nathan A Bruender2, Vahe Bandarian3

  • 1Department of Chemistry, University of California, Davis , Davis, California 95616, United States.

Journal of the American Chemical Society
|January 6, 2018
PubMed
概括

这项研究揭示了一种新型的基因中间体,该基因在6- carboxypterin (6- CP) 由7- carboxy-7- deazaguanine (CDG) 合成酶 (QueE) 的酶转化过程中被发现. 光谱证据证实了6-CP-dAdo基的形成,阐明了罗胺代谢物合成的新反应途径.

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