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Updated: Feb 15, 2026

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
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培养血造干细胞产生抗结核的先天免疫力

Eva Kaufmann1, Joaquin Sanz2, Jonathan L Dunn1

  • 1Meakins-Christie Laboratories, Department of Medicine, Department of Microbiology and Immunology, Department of Pathology, McGill International TB Centre, McGill University Health Centre, Montreal, QC H4A 3J1, Canada.

Cell
|January 13, 2018
PubMed
概括

先天性免疫记忆,以前认为是不可能的,是由培养血造干细胞 (HSCs) 的Bacillus Calmette-Guérin (BCG) 生成的. 这种重编程增强了巨细胞对结核病的保护.

关键词:
一个BCG表观遗传重编程巨细胞结核菌干细胞被训练的免疫力

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