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一个Myc增强剂集群调节正常和白血病造血干细胞等级

Carsten Bahr1,2,3, Lisa von Paleske1,2,3, Veli V Uslu4

  • 1Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ) and DKFZ-ZMBH Alliance, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

Nature
|January 18, 2018
PubMed
概括

一个控制Myc基因表达的关键调控区域,称为血液增强器集群 (BENC),对正常的血细胞发育和骨髓性白血病的维持至关重要. 它的失调会影响干细胞功能和疾病的进展.

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