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Updated: Jan 17, 2026

Promoting 3-D Aggregation of FACS Purified Thymic Epithelial Cells with EAK 16-II/EAKIIH6 Self-assembling Hydrogel
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α-Klotho是FGF23激素信号的非酶性分子支架

Gaozhi Chen1,2, Yang Liu2, Regina Goetz2

  • 1Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.

Nature
|January 18, 2018
PubMed
概括

抑制衰老的α-klotho作为支架蛋白,而不是酶,通过与纤维细胞生长因子受体 (FGFR) 和FGF23结合来促进FGF23信号传递. 这种相互作用对于矿物离子和维生素D的稳态至关重要.

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