积极和消极单体的序列特异性自组与[8]uril链接器
Mersad Raeisi1, Kondalarao Kotturi1, Ian Del Valle1
1Department of Chemistry and Biochemistry , Ohio University , Athens , Ohio 45701 , United States.
Journal of the American Chemical Society
|February 15, 2018
概括
黄瓜[8]uril (CB[8]) 促进了正和负铁复合物的社会自我组合,使其成为异构的动态寡合体. 复杂的可溶性和序列取决于这些连接的金属有机单元的特定排列.
科学领域:
- 超分子化学
- 协调化学
- 材料科学
背景情况:
- [8]uril (CB[8]) 是一种能够与客分子形成复合物的宏循环宿主.
- 迪托普金属双胺复合体为构建有序的超分子结构提供了机会.
- 了解自组装对于设计功能性材料至关重要.
研究的目的:
- 研究[8]uril (CB[8]) 与阳性和阴性铁 bis-terpyridine 复合物的自我组装行为.
- 确定CB[8] 是否在形成异构体中介于社会自我排序模式.
- 分析组合序列对动态寡合物的可溶性的影响.
主要方法:
- 进行光谱分析以确认复杂的形成.
- 动态光散射以评估寡合体大小和可溶性.
- 二维核磁共振 (2D NMR) 用于识别弱相互作用.
主要成果:
- CB[8]成功地将正和负铁单元连接成异性复合体,证明了社会自我分类.
- 在特定条件下 (Fe-Ir-Ir-) n序列占主导地位.
- 观察到酸盐侧链与CB之间的弱相互作用[7],导致轻微的pKa转移.
结论:
- CB[8] 作为一个多功能链接器,促进相反电荷的金属复合物的自我组装成定义的超分子结构.
- 组装的序列显著影响了得到的动态寡合物的宏观性质,例如溶解性.
- 超分子相互作用,包括弱相互作用,在决定最终的结构和特性方面发挥着关键作用.
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