自发早产与未来母亲心血管疾病的关联
Margo B Minissian1,2,3, Sarah Kilpatrick4, Jo-Ann Eastwood3
1Barbra Streisand Women's Heart Center, Cedars-Sinai Heart Institute (M.B.M., J.W., C.L.S., C.N.B.M.) MinissianM@cshs.org.
Circulation
|February 21, 2018
概括
自发早产可能是女性未来心血管疾病风险的信号. 怀孕期间
科学领域:
- 生殖健康
- 心血管医学
- 妇产科
背景情况:
- 已知心血管疾病 (CVD) 的风险因素.
- 怀孕期间的心血管反应是孕妇心血管疾病风险的早期标志.
- 自发早产与母亲心血管疾病死亡的风险增加了三倍.
研究的目的:
- 批判性地评估sPTD与未来母亲心血管疾病风险之间的关联.
- 探索与sPTD相关的心血管疾病风险因素,炎症生物标志物和血管功能障碍.
- 了解将sPTD与未来心血管疾病风险增加的机制.
主要方法:
- 这篇评论批判性地评估了现有的文献.
- 专注于心血管疾病风险因素,炎症生物标志物和血管功能障碍 (内皮功能,动脉硬).
- 检查这些因素与sPTD相关联的机制.
主要成果:
- 在未来,产妇患心血管疾病死亡的风险显著增加.
- 怀孕期间的心血管反应可以作为早期的生理应力测试.
- 潜在的联系包括心血管疾病风险因素,炎症和血管功能障碍.
结论:
- 孕期与未来孕妇心血管疾病风险之间的关联凸显出孕期是潜在的查期.
- 需要进一步研究以阐明机制.
- 了解这些联系可以为心脏病风险较高的妇女提供早期干预信息.
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