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相关概念视频

Chronic Pharyngitis01:23

Chronic Pharyngitis

12.5K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
12.5K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

750
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
750
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

768
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
768
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

816
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
816
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

383
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
383
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

2.6K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.6K

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相关实验视频

Updated: Feb 14, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
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Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation

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慢性淋巴细胞白血病

Michael Hallek1, Tait D Shanafelt2, Barbara Eichhorst1

  • 1Department of Internal Medicine, Center of Integrated Oncology Köln Bonn, University Hospital of Cologne, Cologne, Germany.

Lancet (London, England)
|February 26, 2018
PubMed
概括

慢性淋巴细胞白血病 (CLL) 发病的近期进展已经产生了新的预后工具和向治疗方法,改善了患者的治疗结果. 这一审查涵盖了进展,并讨论了最佳的疾病管理策略.

科学领域:

  • 血液学
  • 癌症学
  • 临床医学

背景情况:

  • 慢性淋巴细胞白血病 (CLL) 是发达国家最常见的白血病,通常在72岁时被诊断出来.
  • 根据Rai和Binet的分期系统和症状的存在来决定CLL的治疗方法.
  • 化疗和抗CD20单克隆抗体是许多CLL患者的标准治疗方法.

研究的目的:

  • 审查最近的CLL管理进展.
  • 突出新的预测工具和针对性的治疗方法.
  • 在最佳的CLL疾病管理中确定新出现的问题.

主要方法:

  • 关于慢性淋巴细胞白血病的最新科学文献.
  • 分析新的预后工具和向治疗方法.
  • 讨论当前和未来的治疗策略.

主要成果:

  • 在了解CLL病变方面取得了重大进展.
  • 开发新的预后工具和向治疗方法 (ibrutinib,idelalisib,venetoclax).
  • 在特定的CLL患者中改善了临床结果.

结论:

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From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
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HPLC-based Assay to Monitor Extracellular Nucleotide/Nucleoside Metabolism in Human Chronic Lymphocytic Leukemia Cells
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Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
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  • 针对性治疗改变了某些CLL患者的治疗标准.
  • 持续的研究对于完善疾病管理至关重要.
  • 需要进一步的研究来解决CLL治疗中的新问题.