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Updated: Feb 13, 2026

Single-Molecule Real-Time Visualization of DNA Unwinding by CMG Helicase
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细胞CMG酶激活的机制

Max E Douglas1, Ferdos Abid Ali2, Alessandro Costa2

  • 1Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.

Nature
|March 1, 2018
PubMed
概括

细胞DNA复制的启动包括两个阶段. 发射因子激活微染色体维护 (MCM) 复合体到两个Cdc45-MCM-GINS (CMG) 基酶,确保精确的DNA复制.

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