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Updated: Feb 13, 2026

Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System
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在蛋白质中功能性替换histidine以产生非正规的氨基酸依赖生物

Fei Gan1, Renhe Liu1, Feng Wang1

  • 1California Institute for Biomedical Research (Calibr) , La Jolla , California 92037 , United States.

Journal of the American Chemical Society
|March 7, 2018
PubMed
概括

研究人员开发了一种方法来创造需要特定非正规氨基酸生长的微生物,从而提高了疫苗和生物制的安全性. 这涉及到用功能模拟物取代必需的histidine氨基酸.

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