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相关概念视频

Encoding01:19

Encoding

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Information enters the brain through encoding, which is the input of information into the memory system. Once sensory information is received from the environment, the brain labels or codes it. The information is then organized with similar information and connected to existing concepts. Encoding occurs through automatic processing and effortful processing.
Automatic processing involves the encoding of details like time, space, frequency, and the meaning of words, usually done without conscious...
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Neuronal Communication01:28

Neuronal Communication

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Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
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Neurons: The Axon01:21

Neurons: The Axon

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Axons are long, cytoplasmic processes of nerve cells capable of propagating electrical impulses known as action potentials. The cytoplasm or axoplasm of an axon contains neurofibrils, neurotubules, small vesicles, lysosomes, mitochondria, and various enzymes, all encased within the axolemma, the plasma membrane of the axon.
The axon attaches to the cell body at a cone-shaped elevation called the axon hillock. The initial part of the axon, closest to the hillock, is known as the initial segment....
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Neuron Structure01:31

Neuron Structure

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Overview
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Neuron Structure01:30

Neuron Structure

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Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
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Adrenergic Neurons: Neurotransmission01:27

Adrenergic Neurons: Neurotransmission

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Postganglionic sympathetic fibers (except those supplying the sweat glands) releasing noradrenaline or norepinephrine are called noradrenergic or adrenergic neurons. Noradrenaline, dopamine, adrenaline, or epinephrine are collectively called "catecholamines" as they contain a catechol moiety and an amine side chain. The five stages of neurotransmitter release involve their synthesis, storage, release, reuptake and metabolism.
Synthesis: Catecholamine synthesis requires tyrosine, which...
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这页已由机器翻译。其他页面可能仍然显示为英文。View in English
  1. 首页
  2. 研究领域
  3. 生物医学和临床科学
  4. 瘤学和致癌症
  5. 预测和预后标志物
  6. 通过双臂神经元编码危险

通过双臂神经元编码危险

Carlos A Campos1, Anna J Bowen1, Carolyn W Roman1

  • 1Howard Hughes Medical Institute and Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA.

Nature
|March 22, 2018

相关实验视频

Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons
08:20

Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons

Published on: March 28, 2016

8.4K
Imaging Mitochondrial Ca2+ Uptake in Astrocytes and Neurons using Genetically Encoded Ca2+ Indicators GECIs
07:46

Imaging Mitochondrial Ca2+ Uptake in Astrocytes and Neurons using Genetically Encoded Ca2+ Indicators GECIs

Published on: January 22, 2022

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Detection and Quantification of Calcitonin Gene-Related Peptide CGRP in Human Plasma Using a Modified Enzyme-Linked Immunosorbent Assay
07:14

Detection and Quantification of Calcitonin Gene-Related Peptide CGRP in Human Plasma Using a Modified Enzyme-Linked Immunosorbent Assay

Published on: June 16, 2023

3.4K

在PubMed 上查看摘要

概括
此摘要是机器生成的。

甲核中的基因相关的神经元 (CGRPPBN神经元) 表示威胁. 这些神经元被危险激活,并在食期间被抑制,

科学领域:

  • 神经科学
  • 行为生物学
  • 感官生理学

背景情况:

  • 需要对各种威胁做出适当的反应.
  • 基因相关 (CGRP) 神经元在核 (PBN) 中参与处理和恐惧行为.
  • 这些不同过程的精确编码机制由CGRPPBN神经元仍然不完全理解.

研究的目的:

  • 研究CGRPPBN神经元在编码与威胁和养行为相关的感官信号中的作用.
  • 确定CGRPPBN神经元如何促进适应性行为状态.

主要方法:

  • 在小鼠中单个CGRPPBN神经元的体内成像.
  • 记录神经元活动对有害皮肤和内脏刺激的反应.
  • 评估神经元在食,腹以及对新食物和条件恐惧刺激的反应.
  • 评估CGRPPBN神经元沉默对食物恐惧和条件恐惧的行为影响.

主要成果:

  • 大多数CGRPPBN神经元被有害刺激 (皮肤和内脏) 激活.
  • 这些神经元在食期间被抑制,但在腹期间被激活,这表明它们在防止过度进食方面发挥了作用.
  • CGRPPBN神经元对新的食物消费和与负面体验相关的听觉线索做出反应.

相关实验视频

Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons
08:20

Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons

Published on: March 28, 2016

8.4K
Imaging Mitochondrial Ca2+ Uptake in Astrocytes and Neurons using Genetically Encoded Ca2+ Indicators GECIs
07:46

Imaging Mitochondrial Ca2+ Uptake in Astrocytes and Neurons using Genetically Encoded Ca2+ Indicators GECIs

Published on: January 22, 2022

4.6K
Detection and Quantification of Calcitonin Gene-Related Peptide CGRP in Human Plasma Using a Modified Enzyme-Linked Immunosorbent Assay
07:14

Detection and Quantification of Calcitonin Gene-Related Peptide CGRP in Human Plasma Using a Modified Enzyme-Linked Immunosorbent Assay

Published on: June 16, 2023

3.4K
  • 沉默CGRPPBN神经元可以减少食物恐惧症和条件恐惧反应.
  • 结论:

    • CGRPPBN神经元对于传感主要危险信号至关重要.
    • 这些神经元在促进情感行为状态方面发挥着重要作用,
    • CGRPPBN神经元整合感官信息来编排适应性生存行为.