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Updated: Feb 12, 2026

High-throughput Nitrobenzoxadiazole-labeled Cholesterol Efflux Assay
08:18

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Published on: January 7, 2019

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胆固醇外流途径抑制炎症酶激活,NETosis和动脉生成

Marit Westerterp1,2, Panagiotis Fotakis1, Mireille Ouimet3,4

  • 1Division of Molecular Medicine (M.W., P.F., A.E.B., M.M.M., W.W., S.A., N.W., C.L.W., A.R.T.).

Circulation
|March 29, 2018
PubMed
概括

胆固醇在骨髓细胞中的积累激活NLRP3炎症体,驱动中性粒细胞活动和动脉硬化斑块的形成. 这一途径在坦吉尔病患者中很重要,突出显示了胆固醇,炎症和心血管风险之间的联系.

关键词:
用ATP结合的卡塞特传送器动脉样硬化胆固醇,高血糖细胞外陷炎症体

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