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Updated: Jul 14, 2026

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
09:53

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Published on: February 6, 2017

HLA-DR1受限制的T细胞抗原识别结构模型

J B Rothbard1, R I Lechler, K Howland

  • 1Laboratory of Molecular Immunology, Imperial Cancer Research Fund, London, England.

Cell
|February 26, 1988
PubMed
概括

研究人员确定了两种关键的流感T细胞决定因素,一种在血凝素中,一种在矩阵蛋白中 (M1). 这些发现揭示了一种特定的螺旋形图案,对于在流感和其他过敏中对DR1-受限制的T细胞识别至关重要.

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