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RBM20突变诱导与处理障碍相关的失律性扩展性心肌病

Maarten M G van den Hoogenhof1, Abdelaziz Beqqali1, Ahmad S Amin1

  • 1Department of Experimental Cardiology (M.M.G.v.d.H., A.B., A.S.A., I.v.d.M., S.A., M.A.F.K., C.A.S., J.A.J., C.A.R., A.o.V., A.B., Y.M.P., E.E.C.), Academic Medical Center, Amsterdam, The Netherlands.

Circulation
|April 14, 2018
PubMed
概括

通过破坏处理,RNA结合动机蛋白20 (RBM20) 的突变增加了扩张性心肌病的失律风险. 这表明ICa,L阻断剂可能对患者有好处.

关键词:
替代拼接心律不整,心脏病没有通道,L型心肌病,扩大人类核酸结合动机蛋白 20

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