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Updated: Feb 11, 2026

miRNA Expression Analyses in Prostate Cancer Clinical Tissues
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癌症生殖线抗原表达对CTLA-4阻断的临床结果产生差异

Sachet A Shukla1, Pavan Bachireddy2, Bastian Schilling3

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Broad Institute, Cambridge, MA 02142, USA.

Cell
|April 17, 2018
PubMed
概括

一个特定的MAGE-A基因特征预测了黑色素瘤中对CTLA-4阻断的抵抗力. 这种耐药性与自抑制有关,表明自诱导是潜在的治疗方法.

关键词:
在 CTLA-4马格-A美国自食症癌症生殖线抗原检查点封锁免疫遗传学免疫疗法伊皮利穆马布黑色素瘤

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