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Updated: Feb 11, 2026

Real-time Imaging of Leukotriene B4 Mediated Cell Migration and BLT1 Interactions with β-arrestin
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GPCR介导的阿里斯激活的分子机制

Naomi R Latorraca1,2,3,4, Jason K Wang2, Brian Bauer5

  • 1Biophysics Program, Stanford University, Stanford, CA, USA.

Nature
|May 4, 2018
PubMed
概括

发现G蛋白结合受体 (GPCR) 如何激活阿斯特林是药物设计的关键. 这项研究揭示了受体核心和尾部独立激活阿斯特林,为偏向的GPCR配体发展提供了新的见解.

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