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相关概念视频

Spinal Cord01:26

Spinal Cord

2.0K
The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
2.0K
The Spinal Cord01:54

The Spinal Cord

31.9K
The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
31.9K
Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

3.6K
The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
3.6K
Spinal Cord: Gross Anatomy01:15

Spinal Cord: Gross Anatomy

5.9K
The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
5.9K
Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

4.9K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
4.9K
Whole Body Regeneration01:33

Whole Body Regeneration

4.2K
Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
4.2K

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相关实验视频

Updated: Feb 10, 2026

Dissection and Culture of Commissural Neurons from Embryonic Spinal Cord
12:23

Dissection and Culture of Commissural Neurons from Embryonic Spinal Cord

Published on: May 25, 2010

17.6K

剖析脊髓再生

Michael V Sofroniew1

  • 1Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. sofroniew@mednet.ucla.edu.

Nature
|May 18, 2018
PubMed
概括

由于神经再生有限,脊髓损伤的恢复仍然具有挑战性. 了解再生失败和成功的机制是推动脊髓损伤治疗的关键.

科学领域:

  • 神经科学
  • 复原医学
  • 脊髓损伤研究

背景情况:

  • 在严重脊髓损伤 (SCI) 后的功能缺陷是长期存在的临床挑战.
  • 尽管进行了数十年的研究,但在SCI中实现显著的神经再生和功能恢复是缓慢和有争议的.
  • 之前的干预措施遭遇挫折,强调需要对再生过程有更深入的了解.

研究的目的:

  • 批判性地检查脊髓再生研究的进展和挫折.
  • 分析SCI当前治疗方法的基本假设.
  • 通过扩大神经再生的机械知识,

主要方法:

  • 对脊髓再生现有文献进行审查和批判性分析.
  • 审查SCI研究中的概念进步和报告的干预措施.
  • 对再生失败和成功的机制基础的评估.

主要成果:

  • 在脊髓再生领域存在持续的挑战和争议.
  • 突出了目前基于错误假设的方法的局限性.
  • 强调需要对再生生物学有更全面的理解.

结论:

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Investigating Functional Regeneration in Organotypic Spinal Cord Co-cultures Grown on Multi-electrode Arrays
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Investigating Functional Regeneration in Organotypic Spinal Cord Co-cultures Grown on Multi-electrode Arrays

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Spinal Cord Transection In Xenopus laevis Tadpoles
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Spinal Cord Transection In Xenopus laevis Tadpoles

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相关实验视频

Last Updated: Feb 10, 2026

Dissection and Culture of Commissural Neurons from Embryonic Spinal Cord
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Dissection and Culture of Commissural Neurons from Embryonic Spinal Cord

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Investigating Functional Regeneration in Organotypic Spinal Cord Co-cultures Grown on Multi-electrode Arrays
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Investigating Functional Regeneration in Organotypic Spinal Cord Co-cultures Grown on Multi-electrode Arrays

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Spinal Cord Transection In Xenopus laevis Tadpoles
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Spinal Cord Transection In Xenopus laevis Tadpoles

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  • 需要对神经再生有更深入的理解.
  • 解决概念上的争议取决于阐明再生为什么失败以及如何恢复.
  • 未来的进步取决于整合不同形式的神经再生的知识.