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全球出现抗真菌药物耐药性,对人类健康和粮食安全构成挑战

  • 0MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London W2 1PG, UK. matthew.fisher@imperial.ac.uk s.j.gurr@exeter.ac.uk.
Clinical Neuroscience (new York, N.y.) +

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概括

此摘要是机器生成的。

致病菌由于广泛应用,正在迅速对广泛使用的抗真菌产生耐药性. 这种抗药性对人类健康,药物和粮食安全构成重大威胁, 需要采取紧急行动.

科学领域

  • 菌群学
  • 抗菌药物耐药性
  • 生物化学

背景情况

  • 抗真菌药物耐药的病原菌的出现正在加速.
  • 在人类/动物健康,农业和工业用途中广泛使用.
  • 醇的广泛使用推动了各种环境中耐药性的演变.

研究的目的

  • 为了强调抗真菌耐药性的前所未有的增长.
  • 强调耐药性机会性真菌病原体带来的风险.
  • 呼吁改善抗真菌管理和创新.

主要方法

  • 关于抗素耐药性的文献综述
  • 对耐药性的环境和临床影响的分析.
  • 综合目前的挑战和未来的战略.

主要成果

  • 由于无处不在的使用,阿醇耐药性正在迅速发展.
  • 机会性真菌病原体对醇的耐药性越来越强.
  • 现有的抗真菌疗法越来越无效.

结论

  • 迫切需要更好地管理当前的抗真菌化学品.
  • 发现新型抗真菌剂至关重要.
  • 需要探索新兴的替代抗真菌解决方案.

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