在MOMENTUM 3长期成果研究中的医疗资源使用和成本影响
Mandeep R Mehra1, Christopher Salerno2, Joseph C Cleveland3
1Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, Boston, MA (M.R.M.).
Circulation
|May 30, 2018
概括
与先进心力衰竭患者相比,HeartMate 3 (HM3) 左心室辅助系统导致住院次减少,并大大节省了成本. 这一经济分析显示HM3
科学领域:
- 心血管医学
- 健康经济学
- 医疗设备技术
背景情况:
- 在MOMENTUM 3试验中比较了离心HeartMate 3 (HM3) 和轴心HeartMate II (HMII) 连续流动的左心室辅助系统.
- 在2年内,HM3在没有致残性中风或重复手术的生存主要终点上表现出优势.
研究的目的:
- 评估HM3与HMII对健康资源的利用和经济影响.
- 在晚期心力衰竭患者中评估两种设备的成本差异.
主要方法:
- 分析出院后的住院费用和相关费用.
- 使用试验数据和索赔数据库计算可归因于设备和不可归因于设备的成本.
- 根据子组进行分层成本节约分析.
主要成果:
- 与HMII相比,HM3组的住院次数较少 (每年患者为2.1人,每年患者为2.7人) 和住院日数较少 (每年患者为17.1人,每年患者为25.5人).
- 在HM3的治疗中,血栓 (0. 6% 与 12. 5%) 和中风 (2. 8% 与 11. 3%) 显著降低.
- HM3 (37,685美元) 的退院后费用比HMII (76,599美元) 每年患者低51%.
结论:
- 与HMII相比,HM3左心室辅助系统减少了再住院和显著的退院后成本节省.
- 这些经济效益与预期的治疗目标 (移植或目的地治疗) 不同.
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